I run the plug-in in Pro Tools LE 7.4 that runs with either a Digi 002R or a Digidesign Micro Box, depending on where I am.
I am currently running the Prosoniq Orange Vocoder on a Mac Book Pro that has a 2.2 Ghz Intel Core 2 Duo processor and 4 GB of RAM. The manual for the software is easy to follow and could be helpful for beginners. The software then has sections for a mixer, reverb, a graphic EQ, and an overall control section, so as you can see this software goes beyond the basic functions and features that you would expect with a vocoder. The software contains an 8 voice synthesizer that has sections for two oscillators, a filter, and a small virtual keyboard. The interface of the software has a lot going on but is definitely easily manageable to figure out as long as you play around with it for a little while as all of the basic functions are easy to find and manipulate. It only took a few minutes and I didn't have any compatibility problems or other issues whatsoever.
The Prosoniq Orange Vocoder was an easy piece of software to install as it was just as easy to install as any other piece of software out there.